Iran launched multiple deadly waves of missiles and drones toward Israel into Saturday morning following Israel’s unprecedented strikes aimed at destroying Iran’s nuclear program and decapitating its military leadership.

The sweeping attacks by Israel, which began early Friday, have killed more than 70 people, including four of Iran’s top security chiefs, and damaged Iran’s main nuclear site at Natanz. Iran retaliated by launching scores of missiles at Israel. At least three people have been killed and dozens more wounded during these attacks.

Follow live updates as Iran retaliates after Israel strikes nuclear facilities. Stay informed with real-time news and developments.

Israel on Saturday threatened to strike "every target of the ayatollah regime" in Iran, whose president warned of a severe response if the Israeli attacks continue, fuelling fears of an escalating conflict.

In sweeping attacks that started early Friday, Israel has struck at the regime in Tehran, targeting Iranian nuclear and military assets. The Israeli strikes have killed more than 70 people, including four top security chiefs, and damaged Iran’s main nuclear site at Natanz.

Defense Sec. Hegseth confirmed that President Trump is "dialed in" to the Israel-Iran conflict on "Fox & Friends" Friday and assured that this is not an "autopen moment" for the president.

Trump told the Wall Street Journal that he knew all about Israel’s plan ahead of time, that he wasn’t given a mere “heads-up.”

Airlines cleared out of the airspace over Israel, Iran and Iraq early on Friday after Israel launched attacks on targets in Iran, Flightradar24 data showed, with carriers scrambling to divert and cancel flights to keep passengers and crew safe.