Karen Read on Tuesday disputed Norfolk Superior Court Judge Beverly Cannone’s claim that jurors in her murder retrial are “fed up” with the case.

For the second time in a week, Judge Beverly Cannone denied Karen Read's attorneys' request for a mistrial after they accused the prosecution of misconduct.

Read’s lawyers again asked Judge Beverly Cannone to issue a finding of not guilty before the case even gets to the jury.

Biomechanical engineer testifies injuries inconsistent with taillight impact in Karen Read murder case, after judge interrupts his birthday message.

Read, 45, is charged with second-degree murder in the death of O’Keefe, who was found outside the home of a fellow Boston police officer on Jan. 29, 2022. Norfolk County prosecutors say Read struck O’Keefe with her SUV while driving intoxicated. Read’s attorneys say her car never struck O’Keefe and that others are to blame for his death.

The judge and lawyers in the second murder trial of Karen Read met Thursday to discuss instructions for the jury, who could begin deliberating Friday.

Judge Beverly Cannone is a breakout star of the Karen Read case. Judge Belvin Perry, who oversaw Casey Anthony's trial, knows that feeling.

Judge Beverly Cannone also denied the defense team’s motion for a mistrial based on what Read’s lawyers called “intentional misconduct” from prosecutor Hank Brennan.