Hosted on MSN20d
Unveiling the intricate mechanisms behind oxysterol-induced cell death
Despite substantial efforts, the molecular mechanisms by which 25-OHC affects glial cells in diseases like amyotrophic lateral sclerosis (ALS) remain unclear. Against this backdrop, a research ...
Nature10y
Oxidation versus aggregation — how do SOD1 mutants cause ALS?
Multiple models have been proposed for the mechanism by which mutant superoxide dismutase 1 induces motor neuron death and amyotrophic lateral sclerosis. A combination of cell biology and genetics ...
QurAlis Announces Topline Data From its Phase 1 Clinical Trial of QRL-101 Evaluating Biomarkers of ALS and Epilepsy in Healthy Volunteers
QurAlis Corporation ("QurAlis"), a clinical-stage biotechnology company driving scientific breakthroughs into powerful precision medicines that have the potential to alter the trajectory of ...