The disruption of axons—the thread-like part of nerve cells that transmits electrical signals—is associated with Alzheimer's disease. One way axonal function may be hindered is through damage to the ...

New research reveals that Alzheimer's disease may impair nerve function not by reducing myelin, but by altering the proteins ...

Importantly, the degeneration of axons and neurons is a major determinant of clinical disease severity in such disorders. It is generally assumed that loss of myelin leads to increased ...

Myelin is an insulating sheath around axons - the processes connecting nerve cells - that is mostly composed of lipids and proteins. It enables rapid conduction of electrical signals and supports ...

What would you see if you cut through an electrical cord? Insulation around the outside and tiny metallic wires stuffed in the middle. The structure of the axons in the nervous system is very similar.

These cells produce the myelin that wraps around and protects axons. This is one of the reasons the myelin sheath is an intriguing area to investigate. Grutzendler’s team, including first author Yifei ...

Comprised of up to hundreds of layers, myelin insulates the axons, as well as shaping them and delivering energy to the axons. (In actuality, a series of such sheaths stretches across the length ...

Myelin is an insulating sheath around axons - the processes connecting nerve cells - that is mostly composed of lipids and proteins. It enables rapid conduction of electrical signals and supports ...

"Our results indicate that iron overload in the oligodendrocytes is an inducer of ferroptosis; physical exercise reduces inflammaging [chronic, low-grade inflammation] and improves axon-myelin ...