It's no coincidence that our bodies feel a little creakier as we age. The trillions of cells that make up our skeleton age too, and some change in ways that weaken the very structure of our bones.

The skeleton is one of the largest organs in the body and is integrated with systemic energy metabolism. This integration is mediated in part through the process of skeletal remodelling, which is ...

Bone density loss is a major concern for astronauts in space, largely due to altered mechanical stimuli in microgravity. These changes are thought to impact bone cells by directly affecting ...

Osteoblasts are specialized bone cells responsible for building and regenerating bone tissue. Researchers at Leipzig University have shown that a specific receptor plays a key role in the strength of ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...

Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells. This vital function is often disrupted in ...

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...

Bone implants often fail to fully integrate with surrounding tissue, limiting their effectiveness in regeneration. A natural but often overlooked cellular process could hold the key to better outcomes ...

The From Labs to Lives Blog connects everyday topics with UC Davis research. Each post is reviewed by our experts, ensuring you always get useful information you can trust. Because we can’t see them, ...