"We therefore looked for ways to shift this ratio in a way that would provide therapeutic benefit," explains Prof. Stoiber-Sakaguchi, who is also the last author of the study. "And we succeeded." The ...

A potential target for experimental drugs that block PRMT5—a naturally occurring enzyme some tumors rely more on for survival—has been identified by researchers with the Fralin Biomedical Research ...

Acute myeloid leukemia, or AML, is a fast-growing cancer of the blood and bone marrow. Although treatment has improved in ...

A HER3-DXd and olaparib combination enhanced DNA damage, apoptosis, and antitumor immune activity in preclinical NSCLC models.

UCLA researchers have identified a promising strategy to make a new class of targeted cancer therapies more effective against one of the deadliest forms of prostate cancer, potentially overcoming ...