Patients with cystic fibrosis who carry the SERPINA1 Z allele have an approximate fivefold increased risk for developing severe liver disease and portal hypertension, according to a new study.

In example 2, only one parent (the father) has a copy of the recessive allele (Ff). There is no chance of them producing a child with cystic fibrosis. However, half the possible offspring will be ...

Porosome Therapeutics, Inc. announced the Orphan Drug Designation of its cystic fibrosis therapy by the Food and Drug Administration (FDA).