Single gene disorders, like Huntington’s disease and cystic fibrosis, actually follow Mendelian ... the PAH-encoding gene was mapped to human chromosome 12 and cloned in 1983.

Cystic fibrosis (CF) is a genetic condition that affects the lungs, pancreas and other organs, caused by variations on the cystic fibrosis transmembrane conductance regulator  (CFTR) gene. There are ...

Cystic fibrosis is caused by hereditary genetic mutations that impair or halt the production of the CFTR protein. The respiratory tract is most severely affected. There, the mucus becomes so ...