Findings from a new Dartmouth-led study, published in the journal mBio, highlight key differences in the gut microbiome (communities of bacteria) of infants with cystic fibrosis (CF) compared to that ...

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Cystic fibrosis (CF) is a single-gene disorder with insufficient treatment options and a target organ, the lung that is relatively easily accessible. Thus, it is not surprising that in the early ...

Despite new medication, cystic fibrosis often leads to permanent lung damage. Working with an international team, researchers ...

Findings from a new Dartmouth-led study, published in the journal mBio, highlight key differences in the gut microbiome ...

Cystic fibrosis transmembrane conductance regulator gene rearrangements were searched ... Three mutations were found as complex alleles (two or three sequence alterations associated in cis on ...

Scientists have created a mega-database revealing how half a million different DNA mutations generate ... such as Huntington's disease and cystic fibrosis. However, in many cases, it's not ...

In their 2019 paper, Liu’s team used prime editing to alter the gene mutations causing sickle cell disease ... a lung biologist and research director at Cystic Fibrosis Trust, who was not involved in ...

The Massachusetts-based biotech plans to use the funds to push its candidates into mid-stage clinical trials in a space ...

Viral and nonviral clinical trials have established proof-of-principle for gene transfer into the cystic fibrosis (CF) lung. It is currently unknown whether gene transfer efficiency is sufficient ...