The genetic disorder cystic fibrosis is unique because it can cause both breathing and digestive problems. Some 40,000 people in the U.S. currently have it, "though this is likely an ...

Established in 2002, the Animal and Preclinical Models Core serves to provide specialized capabilities for developing and characterizing numerous CF animal models relevant to CF pathogenesis and ...

A new study from The Hospital for Sick Children (SickKids) reveals the process underlying protein organization on cell ...

Airway inflammation plays a central role in the pathophysiology of various chronic lung diseases, such as cystic fibrosis (CF), asthma, and chronic obstructive pulmonary disease (COPD).

A recent retrospective study published in CHEST evaluated the effects of cystic fibrosis transmembrane conductance regulator ...

In a recent study published in the Journal of Cystic Fibrosis, Don Ingber and his group at the Wyss ... will allow scientists to better understand CF pathogenesis and screen for more effective drugs ...

John F. Engelhardt, Ph.D., is highly regarded for his research focused on the molecular basis of cystic fibrosis (CF) disease pathologies and on the development of gene therapies for this disorder.

Pinto 1, 71100 Foggia, Italy. Several anatomical and immunological barriers must be overcome before successful gene therapy can become a reality for cystic fibrosis (CF) patients. An approach ...

Radiation-induced fibrosis (RIF) represents one of the most common long-term adverse effects of curative radiotherapy. Current cancer treatment approaches, involving more intensive radiotherapy ...

Porosome Therapeutics, Inc. announced the Orphan Drug Designation of its cystic fibrosis therapy by the Food and Drug Administration (FDA).