Cystic fibrosis (CF) is a rare autosomal recessive disorder that affects numerous systems of the body. It is a complicated disease that differs from person to person. An autosomal recessive disorder ...

Despite new medication, cystic fibrosis often leads to permanent lung damage. Researchers have discovered that the disease causes changes in the immune system early in life, presumably even in ...

Protein clustering mechanism on the cell membrane presents a new therapeutic target for cystic fibrosis. A new study from The Hospital for Sick Children (SickKids) reveals the process underlying ...

Breathing disorders are common in the U.S. with conditions like COPD affecting some 7% of the population and asthma affecting another 10%. Digestive conditions like GERD, acid reflux, Celiac disease ...

Cystic fibrosis is a genetic disorder that affects roughly 40,000 Americans. The condition is caused by a mutation in the patient's cystic fibrosis transmembrane conductance regulator (CFTR) gene, ...

Cystic fibrosis was once a dire, likely deadly diagnosis, destroying a patient's ability to breathe and digest food—but a revolutionary new treatment offers reason for hope. And on Thursday the three ...

The scientific imperative to identify drugs that could repair mutant CFTR presented a formidable challenge. Small molecules that specifically bound and repaired a defective CFTR peptide fold were ...

For decades, lung disease has been the most visible and life-threatening part of cystic fibrosis. People might picture chronic (long-term) cough, breathlessness, recurrent chest infections and oxygen ...

A generic version of a breakthrough cystic fibrosis drug, manufactured in Bangladesh for a fraction of the American price, may give some families around the world an unlikely lifeline. Josua Lottering ...

In an effort to bring transformative therapies to more people living with CF, Vertex developed assays of Fischer Rat Thyroid (FRT) cells to replicate these rare variants, which allows them to study ...

Office was a generous word for the room in which Dr. Mike Welsh did lots of his research. Large closet fits better. Welsh was mostly alone, hunched over specialized microscopic equipment on a ...