The Th1 cytokines, as well as cytotoxic CD8 + T cells, may promote macrophage/microglial activity, which in turn translates into loss of the oligodendrocyte/myelin complex. Multiple sclerosis (MS ...
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Researchers find B cells drive responses of other immune cells, can be modified to prevent multiple sclerosis symptomsMore information: Rui Li et al, Oxidative phosphorylation regulates B cell effector cytokines and promotes inflammation in multiple sclerosis, Science Immunology (2024). DOI: 10.1126/sciimmunol ...
In 2006, six healthy young men were left in intensive care with multiple organ failure as a result of an out-of-control cytokine immune response during a preclinical trial of a new kind of drug.
is the founding member of a novel family of inflammatory cytokines that plays a critical role in the pathogenesis of many autoimmune diseases, including multiple sclerosis (MS) and its animal ...
The interleukin-17 (IL-17) family cytokines are strong inducers of ... rheumatoid arthritis and multiple sclerosis. The landmark discovery that IL-17-producing T cells were central drivers of ...
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