Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

A systematic approach to find substrates, products, functional roles, and selective inhibitors of previously unknown enzymes has been developed. The technique, devised by professor of cell biology and ...

Scientists have sequenced the genomes of nearly 6,900 organisms, but they know the functions of only about half of the protein-coding genes thus far discovered. Now a multidisciplinary effort ...

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. The researchers said the AI tool, ...

October 30, 2008 — A pair of investigators studying HepA-related protein (HARP) ATPase, a protein associated with Schimke immuno-osseous dysplasia (SIOD), have found that the protein functions as an ...

Patients with lupus are at increased risk of heart disease. Exposing endothelial cells -- known to protect against heart disease, in part by producing nitric oxide -- to the serum of patients with ...