A rat with some human genes could provide a better way to test Alzheimer's drugs. The genetically modified rat is the first rodent model to exhibit the full range of brain changes found in Alzheimer's ...

In a new study appearing in the June issue of Nature Methods, UT Southwestern researchers detail how they created 35 new rat "lines," with each type of animal harboring mutations in specific genes.

In this April 24, 2014, file photo, Katie Spring rolls up plastic that was used to cover certain plants during the winter in a field at the Good Heart Farmstead in Worcester, Vt. Spring and her ...

In a striking demonstration of targeted knockout rats, scientists used zinc finger nucleases to deactivate a green fluorescent protein (GFP) transgene, which causes the rats to appear green under ...

Resulting animals had permanent heritable mutations, according to paper in Science. A group of scientists report the creation of the first genetically modified rats using Sangamo Biosciences zinc ...