If the cerebral hemispheres of the forebrain fail to divide properly in an unborn child, this results in holoprosencephaly. An MDC team led by Annette Hammes has discovered candidate genes that can ...

Scientists from Cleveland, Ohio, and Paris, France, reached an important milestone in understanding a molecular cause of a rare, but serious birth defect, Holoprosencephaly. In this February's FASEB ...

We describe the use of preimplantation genetic diagnosis for SHH mutation in a family with holoprosencephaly. The use of this technique, followed by confirmation of mutation-free status by ...