Hereditary axonal peripheral neuropathies comprise a genetically heterogeneous group of disorders that are clinically subsumed under the name of Charcot–Marie–Tooth (CMT) disease type 2 (CMT2).
MONTREAL — Levels of neurofilament light chain (Nfl) may be a biomarker of chemotherapy-induced peripheral neurotoxicity (PIPN), new research suggests. Investigators found Nfl levels increased in ...
Small fiber neuropathy (SFN) is a neurological disorder which primarily affects the small, sensory nerve fibers of the peripheral nervous system. SFN damages either small myelinated (Aδ) fibers or ...
Data presented at Neuroscience 2018 demonstrates genetic deletion of SARM1 protects axons in the central and peripheral nervous systems with a corresponding reduction of blood neurofilament-light ...
Researchers at Washington University School of Medicine in St. Louis are working toward a treatment for neurodegenerative diseases that targets SARM1, a key molecule in the death of axons, the wiring ...
Peripheral neuropathy (PN) is a dose-limiting side effect of chemotherapeutic and antibody drug conjugate (ADC) treatment which significantly impacts patients’ quality of life. Despite a high clinical ...
Small Fiber Neuropathy (SFN) is a disorder in which the small diameter sensory myelinated (Aδ) and unmyelinated (C fiber) nerves of the peripheral nervous system are damaged. The peripheral nervous ...
(RTTNews) - Clinical-stage gene therapy company Taysha Gene Therapies, Inc. (TSHA), Tuesday announced that the company will discontinue the development of its TSHA-120 program in evaluation for the ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of ...
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