CARD14 directly binds and regulates MYC, a protein involved in controlling cell growth that can contribute to cancer when it malfunctions. A study published in Cell Reports shows that the proper ...

Beyond direct approaches, the review also emphasizes indirect targeting strategies, including inhibition of MYC transcription or translation, promotion of protein degradation, and synthetic ...

Showing great promise in preclinical studies, PMR-116 disrupts a pathway downstream of MYC, inhibiting an enzyme that stunts the synthesis of ribosomal RNA (rRNA) – a process that's crucial in protein ...

Burkitt's lymphoma is a rare and aggressive blood cancer characterized by a translocation of the MYC gene. It occurs most ...

Scientists have learned that prostate cancers can vary significantly among patients and that there are often differences within each patient's tumor. However, the study published Aug. 28 in Nature ...

Our skin–the body's largest organ–provides the first line of defense against infections and many other threats to our health. Decades of research has shown that a wide range of diseases can occur, or ...

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. The poor prognosis is due in part both to late detection and the cancer’s capacity to adapt and ...