The name multiple sclerosis refers to scars (scleroses—better known as plaques or lesions) particularly in the white matter of the brain and spinal cord, which is mainly composed of myelin.

Multiple sclerosis, or MS, is a chronic neurological disease that impacts the brain, spinal cord, and central nervous system. Your brain uses electrical signals to communicate with your body.

More information: Aletta M. R. van den Bosch et al, Profiling of microglia nodules in multiple sclerosis reveals propensity for lesion formation, Nature Communications (2024). DOI: 10.1038/s41467 ...

There’s no single test that can diagnose multiple ... active lesions often show inflammatory demyelination, while old lesions may show scarring that is often described as “sclerosis.” ...

Scientists in Sweden were able to uncover the molecular mechanisms behind the development of lesions in multiple sclerosis by employing sophisticated techniques. The latest findings are detailed in ...

Positive spinal cord MRI (≥ 2 focal T2 lesions); c. Positive CSF Table used with permission: National Multiple Sclerosis Society Research Bulletins. International panel updates diagnostic ...

A Phase 2 clinical trial testing obexelimab in adults with relapsing types of multiple sclerosis is now recruiting ...

Currently, patients with clinically isolated syndrome (CIS) and brain lesions on MRI suggestive of multiple sclerosis (MS), are offered a confirmatory MRI scan after 6 months. Researchers in Italy ...

Multiple sclerosis (MS) is one of the most widespread ... and neurons in the brain and spinal cord. Together these make up the central nervous system. Researchers speculate that a combination ...

Intravenous; MS: Multiple sclerosis ... multiple sclerotic lesions or plaques disseminated throughout the brain and spinal cord, and remarkable disease heterogeneity with variable presentations ...

Multiple sclerosis is a chronic and potentially debilitating ... that surrounds nerve cells in the brain and spinal cord. When this lining becomes inflamed or destroyed, it slows down and disrupts ...