Scientists have long believed that disease-causing genetic variants inevitably lead to disease. But a sea change of research ...

Two groups studied the same cancer mutations in the blood. They agreed on many aspects, including the mechanism at work. But ...

Nearly every cell in the human body contains essentially the same genetic information, yet different cells activate different ...

You are what you eat, but what happens to those calories after you eat may depend more on your genes than you think.

A previously missed mutational signature in colorectal cancer has been identified. The discovery could provide new insights ...

A domestic research team is developing an anticancer technology that identifies and removes DNA mutations found only in ...

A study found that an LRRK2 mutation associated with Parkinson’s disease strengthens neutrophils’ antibacterial activity, ...

Innovative research led by a University of Ottawa Faculty of Medicine professor whose lab focuses on mechanisms that maintain ...

DNA has to be interpreted by cells. The letters or bases that make up genetic sequences are read in sets of three, and those three-base sequences are known as codons. Every codon encodes for one amino ...

Rerunning tumour evolution in mice shows how cancer develops after DNA damage and reveals that background genetics and acquired mutations interact to shape genome stability and selection. This ...

Human cells usually contain two copies of most genes, one of which comes from the mother while the other comes from the father. It's long been thought that usually these two copies, or alleles of ...