In the PNS, one Schwann cell forms a single myelin sheath (Figure 1A). By contrast, in the CNS, the oligodendrocyte sends cell processes to myelinate multiple segments on many axons (Figure 2).

That myelin sheath degrades in CMT1A. Because the PMP22 protein is produced by Schwann cells, that's where the lab of Prof. Ludo Van Den Bosch (VIB-KU Leuven Center for Brain & Disease Research ...

Myelin – produced by Schwann cells in the periphery and oligodendrocytes in the CNS – is defective in diseases such as multiple sclerosis, and many myelin repair strategies aim to mitigate ...

This illustration shows the proposed role of myelinophagy in a Schwann cell after nerve injury and axon degeneration (right). The myelin sheath breaks up into fragments in the cytoplasm that are ...

Myelin is an insulating layer of lipids and proteins surrounding nerves. Myelin damage can cause problems with the nerves’ ability to send and receive electrical messages. Inflammatory disorders ...

They are often between the ages of 30 and 60. Acoustic neuroma tumors begin in what are called Schwann cells. These cells make myelin, which is the material that insulates and protects the nerves ...

In a test tube, AMPK activation reversed insulin resistance in Schwann cells, which form the myelin sheath that cover the nerves. "Taken together, these results help us understand how peripheral ...

Damage to myelin around nerves is called demyelination. Demyelination can cause issues like: The axon sends messages from one neuron to the next and connects neurons to other cells, such as muscle ...

These join to other nerve cells, allowing them to pass messages around the body. They have a fatty (myelin) sheath that surrounds them. The fatty sheath increases the speed at which the message ...

Moreover, because myelin is produced by non-neuronal glial cells called oligodendrocytes, which myelinate axons by extending thin processes of their cell membranes to wrap around them, the study ...