In individuals with multiple sclerosis (MS), abnormally active respiration in B cells drives pro-inflammatory responses of myeloid cells and T cells, leading them to attack the protective sheath ...

a proinflammatory cell type that is thought to contribute to multiple sclerosis. These reports clearly establish a central role for myeloid APCs, including macrophages and microglia, in immune ...

Autoimmune conditions such as multiple sclerosis (MS ... This is the process through which these cells differentiate towards the myeloid lineage, ending up resembling naïve microglia.

Multiple sclerosis (MS) is considered to be a predominantly T-cell-mediated disease, and emerging evidence indicates that dendritic cells have a critical role in the initiation and progression of ...

Use this guide to learn how B-cell therapy may help with your multiple sclerosis, along with what to consider if you’re already on it.

Myeloproliferative neoplasms are blood cancers that affect myeloid stem cells. Treatment can involve targeted medications or careful monitoring. Myeloproliferative disorders are a group of cancers ...

Multiple myeloma (MM) invariably develops in the bone marrow (BM), indicating the strong requirement of this tumor for the peculiar BM microenvironment, rich in cytokine and hematopoietic ...

Blood tests often show a high white blood cell or lymphocyte level. You’d get more tests to find out if this is leukemia. Two other types of leukemia -- acute myeloid leukemia (AML) and chronic ...

and Multiple Sclerosis, in comparison to healthy controls. The findings reveal nine subpopulations, demonstrating that microglia exist under the form of transcriptionally distinct groups of cells.

MP-specific IL-10-producing cells were also upregulated, and were shown to have reduced IFN-γ production and to lack apoptotic activity. [80] Multiple Sclerosis Center of Catalonia, Vall d'Hebron ...