High levels of calcium are toxic to cells and contribute to loss of neurons in Alzheimer’s disease. A new JCI Insight study ...

Neuronal calcium sensors (NCS) comprise a pivotal family of EF‐hand calcium‐binding proteins that translate transient fluctuations in intracellular Ca²⁺ into specific cellular responses. These ...

When triggered by an odor, rapid changes in membrane voltage and intracellular calcium ion levels occur in nematode olfactory neurons, causing membrane voltage sensors and calcium ion sensors to ...

Calcium in the mitochondria -- the energy factory of cells -- may be one of the keys to understanding and treating Alzheimer's disease and dementia. Researchers at the Center for Translational ...

Astrocyte activity precedes the onset of epileptic neuronal hyperactivity episodes. (A) With cytosolic calcium ion increase, excitatory actions from astrocytes to neurons are likely to be initiated.

Researchers have discovered how an ion channel in the brain's neurons has a kind of 'molecular memory', which contributes to the formation and preservation of lifelong memories. The researchers have ...

In cell signaling, calcium is king. The flux of calcium ions across cell membranes regulates cellular activities from muscle contraction to neuron firing to immune cell function. A talk I saw here at ...