A 73-year-old lady was referred complaining of a 2-month history of reduced central vision in the right eye. Her left vision had been poor since childhood and she had not noticed a change. She was ...

Osteogenesis imperfecta (OI) is a heterogeneous group of genetic disorders that affect connective tissue integrity. The hallmark of OI is bone fragility, although other manifestations, which include ...

Could you describe the events leading up to your diagnosis? When I was born, both my femurs were fractured. But, I had normal height and weight, so the doctors struggled to find out what was going on.

Fragile bones make us think of old people. But there are children who are born with bones so weak that even the slightest fall or sneeze can break them. Such a condition is named Osteogenesis ...

Osteogenesis imperfecta (OI) causes bones to be fragile and easily broken and is also responsible for other health problems. Type I OI is the mildest form of the condition. People who have type I OI ...

Osteogenesis Imperfecta (OI) is a genetic disorder that impacts thousands of families across the world. Also known as brittle bone disease, OI is characterized by bones that do not form normally or ...

The main feature of osteogenesis imperfecta is the widely prevalent fragility of the bones, which makes them fracture-prone. These fractures, when they occur, heal properly, but again the new bone ...

Dear Dr. Roach: What's the best way to obtain and maintain healthy, white sclera? Mine appears to be a light, off-white gray. -- M.T. Dr. Roach: Sclerae, the whites of the eyes, tend to thin with age ...