Another obstacle to gene therapy arises from the fact that rAAV vectors less effectively transfect outer hair cells (OHCs) than inner hair cells (IHCs). 3 This is a major limitation because OHCs are ...
Radiation Research, Vol. 150, No. 1 (Jul., 1998), pp. 31-37 (7 pages) Replication-deficient adenovirus (Adv5)-based vectors containing either wild-type p53 or the β-gal marker gene were introduced ...
Scientists have developed "the double viral vector transfection technique," which can deliver genes to a specific neural circuit by combining two new kinds of gene transfer vectors. With this method, ...
AUSTIN, Texas & CAMBRIDGE, Mass.--(BUSINESS WIRE)--Genprex, Inc. (NASDAQ: GNPX), a clinical-stage company and leader in gene therapy using non-viral vector transfection delivery, wishes to draw ...
Gene therapy involves the transfer of genetically modified materials into a patient's cells to correct abnormal genes associated with diseases (Sun, 2017). Recent advancements in gene therapy have ...
Academic research trends continue to drive transfection technology advancements. Researchers hope to use more biologically relevant yet hard-to-transfect cell models in addition to the standard ...
Immunotherapies against cancer, vaccines against new viruses (or old viruses in new places), and attempts to resolve pathogenic single-cell defects—all are looking to incorporate transfection ...
Transfection alters the genetic makeup of eukaryotic cells by introducing foreign nucleic acids, including DNA, RNA, and small noncoding RNAs such as siRNA, shRNA, and miRNA. Scientists use ...
Hinnah Campwala (left) is a Principal Scientist in the Cell Biology Development Group at Sartorius BioAnalytical Instruments (Michigan, USA). With a background in drug discovery and immune cell ...
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