NEW YORK (WABC) -- Manuel Greco has Von Hippel-Lindau disease. It's a rare condition that causes tumors to grow in certain parts of the body. Most of the tumors are benign but they often grow back ...

Decision marks first approval for WELIREG in China and 17th approval of WELIREG for these patients globally In August 2021, WELIREG was approved in the U.S. for the treatment of adult patients with ...

A multicenter Phase II clinical trial led by researchers at The University of Texas MD Anderson Cancer Center demonstrated ...

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...

Patient-reported outcomes (PROs) for tivozanib (TIVO) + nivolumab (NIVO) vs TIVO monotherapy in patients with renal cell carcinoma (RCC) following an immune checkpoint inhibitor (ICI): Results of the ...

A multicenter Phase II clinical trial led by researchers at The University of Texas MD Anderson Cancer Center demonstrated ...

The EC conditionally approved Merck’s Welireg for certain VHL disease-associated tumors and advanced RCC after two or more prior treatments. Approval is based on data from the LITESPARK-004 and ...

The familial cancer syndrome, von Hippel–Lindau (VHL) disease, characterized by a predisposition to renal cell carcinoma and certain other tumor types, is caused by mutational inactivation of the VHL ...

New insights into the biology of kidney cancer, including those informed by scientific discoveries that earned a Nobel Prize, have led to advances in treatment and increased survival rates. New ...

The cause of von Hippel–Lindau disease is excess activity of the HIF-2α pathway. A total of 61 patients with renal cell carcinoma and other proliferative manifestations of the hypoxia-induced ...

After being dealt a life-altering diagnosis in May 2018, Ian Phillips realized he had two options: sulk over the news or move forward with a positive attitude. Phillips chose the latter, remaining ...

WELIREG is the first and only systemic therapy approved in China for adult patients with certain VHL disease-associated tumors Decision marks first approval for WELIREG in China and 17th approval of ...