Andrew J. Bett, Wael Haddara, Ludvik Prevec, Frank L. Graham, An Efficient and Flexible System for Construction of Adenovirus Vectors with Insertions or Deletions in Early Regions 1 and 3, Proceedings ...

We have developed adenoviral vectors with a prostate-specific two-step transcriptional amplification (TSTA) system that would express therapeutic genes at a robust level to target metastatic disease.

In addition, some studies have reported different distribution profiles of viral vectors in the central auditory system after a cochlear inoculation.