In samples of the spinal cord from four deceased MS patients, 260 genes were simultaneously analyzed and the cellular architecture of the lesions could be determined.

Multiple sclerosis is an autoimmune disease with progressive stages and types. ... Spinal cord involvement results in slowly worsening leg stiffness, walking problems, and fatigue. ... Gross HJ, ...

Again, the aggregates in the spinal cord were smaller in size compared to the aggregates observed in the corresponding brain. Additionally, massive infiltration of the CNS by immune cells, including ...

Spinal cord involvement is an important cause of disability in patients with multiple sclerosis or neuromyelitis optica spectrum disorders (NMOSDs). Multiple sclerosis and NMOSDs can be distinguished ...

Figure 3. Staining of CD3 + T cells (A), Iba1 + macrophages/microglia (B), and myeloperoxidase-positive neutrophils (C,D) in cervical spinal cord sections from EAE rats.Representative images of ...

The authors show that conditioned medium from human mesenchymal stem cells reduces functional deficits in an animal model of multiple sclerosis and promotes the development of oligodendrocytes and ...

In Panel E, an electron micrograph from an actively demyelinating lesion in the spinal cord of a mouse with acute experimental autoimmune encephalitis, an animal model of multiple sclerosis, shows ...

MERRILLVILLE - Dovette Reilly of Cedar Lake isn't just worried about herself. She's also worried about her mother, her sister and her brother.

The knowledge concerning global ischemia of the spinal cord is based on individual case reports 13,14,18–22,29,35 or studies of small numbers of patients. 6,7,15–17,23–25,34,36 Our results confirm ...