DUBAI, United Arab Emirates (AP) — Israel launched an expanded assault on Iran on Sunday, with direct strikes targeting its energy industry and Defense Ministry headquarters, while Tehran unleashed a fresh barrage of missiles blamed for the deaths of four people and injuries of many others.

Separately in the city’s south, Shahr Rey, one of the country’s largest oil refineries, was also struck, according to Iranian state news media. Emergency crews were trying to contain the fire, and a resident of Tehran, Reza Salehi, said he could see the flames from miles away.

Smoke and flames filled the sky over Tehran as Israel struck oil and gas facilities in the Iranian capital and targeted more nuclear facilities during attacks that carried on into Sunday after starting two days earlier.

Several people were killed when Iran fired a barrage of projectiles at Israel in retaliation for Israel's surprise attack on its foe’s nuclear facilities and military leadership. Follow along for live updates,

Israel warns "Tehran will burn" if Iran continues firing missiles, while state media say 60 people have been killed in a strike on Iran's capital.

Anger is mixed with worry as Iranians in the capital of Tehran woke up Saturday to images of their country’s retaliatory attacks on Israel.

Israel's widespread airstrikes on Iran effectively damaged the country's nuclear and ballistic missile programs, which officials said was a primary goal. The strikes hit over 100 targets, including Iran's air defense systems,

Israel’s historic strike on Iran revealed years of Mossad activity inside the country, including hidden weapons, drones and assassinations of nuclear officials.