Some 17 million Americans are living with genetic mutations tied to an increased risk of getting cancer, Cleveland Clinic ...

Summer McKesson’s quest for answers to her medical condition would unearth a family secret – and a doctor’s decades-old ...

Breast cancer affects many women globally. While most cases are random, some stem from inherited genes like BRCA1 and BRCA2. A family history of breas ...

Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead and senior authors of a paper published in Neuron, "The Gain-of-Function ...

In a study published in Neuron, a research team at the Department of Neurology at Massachusetts General Hospital, aimed to understand how immune cells of the brain, called microglia, contribute to ...

Men with BRCA1 and BRCA2 gene mutations should be given annual prostate cancer screening checks, leading scientists have said. Experts at the Institute of Cancer Research (ICR) in London said men with ...

Summary: Groundbreaking research has revealed that as men age, harmful genetic mutations in sperm not only accumulate but are also favored during sperm production, giving them a reproductive advantage ...

Get ready, because "Father Figure" is about to become one of the most debated songs on Taylor Swift's new album The Life of a Showgirl. There are already theories swirling around about who the song is ...

Parkinson's disease causes both movement and cognitive deficits, and for a long time both were thought to be caused by the accumulation of a protein called alpha-synuclein in the brain. But a new ...

Devin Sidell, a filmmaker and actress, tested positive for the BRCA genetic mutation after her mother had ovarian cancer and her sister had breast cancer She had a preventative double mastectomy, ...

The experiments were carried out with human ENaC. α-ENaC was transcribed from the pSDEasy vector, which was linearized with BglII (Cat #R0144L, New England Biolabs). β-ENaC was transcribed from the ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...