More than 50% of patients with systemic lupus erythematosus (SLE) develop lupus nephritis (LN) during the disease, which may ...

July 10, 2024 — Scientists have discovered a molecular defect that promotes the pathologic immune response in systemic lupus erythematosus (known as lupus) and show that reversing this defect ...

Mass General Brigham researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery ...

The odds of developing systemic lupus erythematosus or systemic sclerosis appear to significantly increase with the use of ...

Interferon-alpha activity may be used routinely in clinical settings as a biomarker for cutaneous lupus erythematosus and ...

Best-in-Class Design to Enhance Therapeutic Benefit and Expand Treatment Potential Across a Range of Autoimmune Disease Indications; Inno ...

Hypoglycemia is a possible but uncommon symptom of systemic forms of lupus, like SLE. Symptoms of hypoglycemia may include lightheadedness, blurred vision, or shaking. Lupus can indirectly cause ...

Long-term use of glucocorticoids (GCs) for the treatment of lupus is very common, however, it has also been associated with side effects like high blood pressure, diabetes, infection, and osteoporosis ...

China Systemic lupus erythematosus (SLE) is a chronic, inflammatory, and progressive autoimmune disease. The unclear pathogenesis, high heterogeneity, and prolonged course of the disease present ...

Rep. Elise Stefanik (R-N.Y.), President Donald Trump’s nominee to represent the U.S. at the United Nations, on Tuesday painted the international organization as a body beset by bias against ...

Research over the past decade has revealed multiple potential mechanisms by which dendritic cells contribute to the immunopathogenesis of systemic lupus erythematosus. Genetic abnormalities in ...

RG-6382 is under clinical development by F. Hoffmann-La Roche and currently in Phase I for Systemic Lupus Erythematosus. According to GlobalData, Phase I drugs for Systemic Lupus Erythematosus have a ...