Background Abnormalities of type I interferon signaling and production can initiate lupus development. Disturbances of nucleic acid-sensing molecules triggered autoreactivity in lupus mouse models.

Lupus can be debilitating and sometimes deadly for the 3 million people who have it. A treatment called CAR T appears to stop ...

Lupus, an autoimmune disorder, presents skin manifestations like the butterfly rash, often mimicked by conditions such as ...

Background An increased risk of malignancy was reported in patients with Systemic Lupus Erythematosus (SLE) [1-3]. Objectives To estimate the prevalence of cancer in a Portuguese cohort of patients ...

Inflammation affects up to 93% of people diagnosed with lupus, and red spots and butterfly rashes are the first sign in up to 25% of people with the disease. ... Mortality in systemic lupus ...

systemic lupus erythematosus; autoantibodies; autoimmune diseases; In their letter,1 Drs Pisetsky, Spencer, Rovin and Lipsky very appropriately continue a highly relevant discussion on anti-nuclear ...

Systemic lupus erythematosus (SLE), an autoimmune disease with heterogeneous clinical manifestations, is associated with significant morbidity and mortality. 1–3 Any organ can be affected in SLE, but ...

Systemic lupus erythematosus (SLE) is the paradigm of systemic autoimmune diseases characterised by a wide spectrum of clinical manifestations with an unpredictable relapsing-remitting course. The aim ...

It is often associated with other forms of cutaneous lupus, and about 20% of patients develop systemic lupus erythematosus(SLE). The patient usually comes with symptoms of purple plaques or nodules ...

Objective To evaluate the risk of stroke and myocardial infarction (MI) in adult patients with systemic lupus erythematosus (SLE) through a systematic review and meta-analysis.Methods We searched ...