It's not looking good for the 49ers and their star receiver, so where do they go from here to save their postseason hopes?

The 49ers kept the score close until early in the fourth quarter on Sunday, but it was a rough day all-around in the 28-18 ...

The biggest concern from Sunday's loss to the Kansas City Chiefs—besides the San Francisco 49ers' falling to 3-4 on the ...

San Francisco 49ers head coach Kyle Shanahan discusses Sunday’s 28-18 loss to the Kansas City Chiefs, believes that Brandon ...

San Francisco 49ers star wideout Deebo Samuel left his team's home game against the Kansas City Chiefs on Sunday with an illness and was later ruled out.

The San Francisco 49ers just lost yet again to the Kansas City Chiefs, this time by a score of 28-18. Here are the 49ers' grades for this embarra ...

San Francisco 49ers wide receiver Brandon Aiyuk left Sunday's game with a knee injury and has been ruled out for the remainder of the contest. Aiyuk ...

Brock Purdy’s three interceptions for the 49ers with no touchdown passes led to a career-low 36.7 passer rating.

Kyle Shanahan evaluated the team's Week 7 loss to the Kansas City Chiefs and shared postgame injury updates on WR Brandon Aiyuk and others.

The San Francisco 49ers' Super Bowl hangover isn't going away easily, with the Kansas City Chiefs sending them below .500 on ...

Already missing one of their top three receivers, the 49ers ruled out Brandon Aiyuk (knee) and Deebo Samuel (illness) for the ...

The 49ers were without three of their top playmakers for much of the matchup, with running back Christian McCaffrey (Achilles ...