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  1. Prostaglandin E2 - Wikipedia

    Prostaglandin E2 (PGE2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. [2][3][4] Dinoprostone is used in labor …

  2. Role of prostaglandin E2 in tissue repair and regeneration

    Prostaglandin E2 (PGE2), which involves diverse physiological processes via E-type prostanoid (EP) receptor family, favors the regeneration of various organ systems following injury for its …

  3. A single dose of a molecule that dwindles in aging restores long …

    Jun 24, 2025 · Essentially, a single injection of PGE2 brokers the exchange in muscle stem cells of a lifetime’s worth of genetic bookmarks and dog-eared pages for a crisp new set of …

  4. Prostaglandin E2 - an overview | ScienceDirect Topics

    Prostaglandin E2 (PGE2) is a cellular mediator with variable pro-inflammatory and anti-inflammatory effects, but in the airway predominantly curbs inflammation. It does this in part …

  5. What are PGE2 agonists and how do they work? - Patsnap

    Jun 21, 2024 · Prostaglandin E2 (PGE2) is a bioactive lipid that plays a pivotal role in a wide array of physiological processes. Its effects are mediated through four distinct receptor subtypes: …

  6. Researchers reverse muscle stem cell aging with Prostaglandin E2

    Jun 13, 2025 · Wang and colleagues at Stanford University published findings June 12, 2025, in Cell Stem Cell demonstrating the effectiveness of treating aged mice with a naturally occurring …

  7. Prostaglandin E2 - American Chemical Society

    Jul 10, 2017 · In 1962, Swedish biochemist Sune Bergström, another Nobel laureate, and his co-workers identified prostaglandin E 2 (PGE2) in the seminal vesicle tissue of sheep. According …

  8. Prostaglandin E2 (PGE2): A Key Mediator of Inflammation and ...

    Prostaglandin E2 (PGE2) a bioactive lipid mediator, for regulating inflammation and immune reactions as well as various bodily functions is derived from arachidonic acid via the …

  9. The Signaling Pathway of PGE2 and Its Regulatory Role in T Cell ...

    Nov 26, 2021 · As an essential inflammatory factor, PGE 2 has a critical impact on immune regulation through the prostanoid E (EP) receptor pathway. T cells, including CD4 + and CD8 …

  10. Prostaglandin E2 - an overview | ScienceDirect Topics

    Among prostaglandins, prostaglandin E2 (PGE2) is the most abundantly produced in cartilage and is capable inducing chondrogenic differentiation of stem cells in vitro in a dose-dependent …