Apoptosome Formation
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Apoptosome Formation
A brief introduction to Caspase-mediated formation and activation of the apoptosome. Cytochrome c released from the mitochondria during apoptosis leads to amplification of the caspase signaling cascade via formation of the apoptosome. A radially-symmetric structure, the apoptosome assembles upon binding of cytochrome c (blue) to Apaf-1 (beige ...
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